A Guide to Wearable-Enabled Digital Clinical Measures in Neuroscience

Overview

Neurological diseases are inherently complex, and drug development in neurology is notoriously challenging. The imprecision of both disease diagnosis and symptom monitoring presents additional hurdles for clinical development. Traditional measures based on subjective rating, either done by clinicians or patients, are susceptible to rater bias and are often sampled between long intervals of time.  On the other hand, digital assessments of function, as quantified from smart sensor data, can provide frequent, objective, and precise measures of how participants function in their real lives. With the ability to collect continuous digital data remotely and passively, wearable devices can improve patient-centricity and reduce trial burden on patients.

What You'll Learn

In this eBook, we explore how digital clinical measures enabled by wearables provide meaningful insights into real-world function and disease progression across the spectrum of neurological disorders, including:

• Movement disorders
• Neurodegenerative disorders
• Neuromuscular disorders
• Psychiatric conditions
• Chronic pain